World Mitochondrial Disease Week, 15 to 21 September 2025

World Mitochondrial Disease Week takes place from 15 to 21 September 2025. It aims to improve the lives of people affected by mitochondrial diseases (mito) and to increase awareness among doctors and the general public. (Mitochondrial myopathies are a subgroup of mitochondrial disease that primarily affect muscle function and lead to muscle weakness, muscle fatigue, and exercise intolerance.) This year's official theme is: Decode the Mito Puzzle – Bridging Science and Symptoms. Mitochondrial diseases are a complex set of conditions that are often misunderstood. Because symptoms vary widely and are linked to individual genetic changes, each patient presents a unique medical puzzle. This year’s theme focuses on connecting scientific understanding with the lived experiences of patients to improve diagnosis, care, and long-term outcomes. The campaign raises awareness of the vital role genetics plays in mitochondrial diseases, the importance of early detection and testing, and the promise of new research. By translating science into real-world solutions, we can empower families, support clinicians, and bring hope to everyone affected by mitochondrial diseases.